To efficiently offer genetical patient care in "the Next Generation Sequencing Era", is sharing genetic data essential. The datashare workgroup of VKGL has set up a central database to enable mutual sharing of variant classifications through a partly automatic process. An additional goal is the public sharing of these data. The currently publicly available part of the database consists of DNA variant classifications established based on (former) diagnostic questions. The database is not a patient database and therefore does not contain any data regarding patients themselves, neither information about in how many patients a DNA variant was seen, nor which clinical features were reported during application.